Sternal Resection and Reconstruction With a Novel Modularized Prosthesis.

Abstract

Currently available techniques and materials for sternal reconstruction are limited in their clinical applicability. We aimed to design a durable prosthetic kit that can be tailored to each patient's sternal anatomy and function intraoperatively. A modularized sternal reconstruction system was designed, containing standardized components of different types and sizes, made of titanium alloy. This technology was applied to patients undergoing sternal resection and reconstruction. The system was employed in 7 patients undergoing sternal resection and reconstruction for local malignancy. Appropriate modules were chosen and integrated at the time of operation. The sternal prostheses were well integrated into the chest wall, without local infection, effusion, or instability. One patient died of recurrence 4 months after surgery. The remaining 6 patients recovered well, without local recurrence or prosthesis failure. The most prominent advantage of this system is that there is no need for individualized design and manufacture before surgery. Therefore, this modularized system is potentially widely applicable as an adaptable and effective prosthesis for sternal reconstruction.