Rubbing Out Leukemia Stem Cells by Erasing the Eraser.
editorial · Level V
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- Record sourced from PubMed, PMID 32619516.
- Also identified by DOI 10.1016/j.stem.2020.06.009 and PMC identifier 9310347.
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Abstract
In this issue of Cell Stem Cell, Shen et al. (2020) and Wang et al. (2020) independently identify the essential function of m<sup>6</sup>A demethylase ALKBH5 in maintaining myeloid leukemia stem cells. These studies expand the regulators of the epitranscriptome that are required for acute myeloid leukemia (AML) development.
Medical subject headings
- Cell Self Renewal
- Leukemia, Myeloid, Acute