Finding the Sweet Spot: Parsing Tissue-Specific Contributions of Fructose Metabolism.

Tesz, Gregory J; Bence, Kendra K · Cell Metab · 2020

editorial · Level V

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Abstract

The abundance of dietary sweeteners and overconsumption of fructose are widely thought to promote metabolic disease. In this issue of Cell Metabolism, Andres-Hernando et al. (2020) identify the liver as the major site of fructose metabolism-mediated metabolic dysfunction and identify a surprising role for intestinal fructose metabolism in driving fructose intake.

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