Constitutional Thinness: tALKing the tALK or wALKing the wALK?

Tung, Y C Loraine; O'Rahilly, Stephen · Cell Metab · 2020

other · Level V

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Abstract

In a recent issue of Cell, Orthofer et al. (2020) present a body of data from mice, flies, and humans that suggest (1) a physiological role for Alk in the normal control of energy balance across several species and (2) a possible contribution of genetic variants in or near ALK to the variability of adiposity in humans, more specifically at its lower end.

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