Estimating the efficacy of symptom-based screening for COVID-19.

Callahan, Alison; Steinberg, Ethan; Fries, Jason A; Gombar, Saurabh; Patel, Birju; Corbin, Conor K; Shah, Nigam H · NPJ Digit Med · 2020

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Abstract

There is substantial interest in using presenting symptoms to prioritize testing for COVID-19 and establish symptom-based surveillance. However, little is currently known about the specificity of COVID-19 symptoms. To assess the feasibility of symptom-based screening for COVID-19, we used data from tests for common respiratory viruses and SARS-CoV-2 in our health system to measure the ability to correctly classify virus test results based on presenting symptoms. Based on these results, symptom-based screening may not be an effective strategy to identify individuals who should be tested for SARS-CoV-2 infection or to obtain a leading indicator of new COVID-19 cases.