Making Sense of Mutation: What D614G Means for the COVID-19 Pandemic Remains Unclear.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 32697970.
- Also identified by DOI 10.1016/j.cell.2020.06.040 and PMC identifier 7332445.
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Abstract
In this issue of Cell, Korber et al. found that a SARS-CoV-2 variant in the spike protein D614G rapidly became dominant around the world. Although clinical and in vitro data suggest that D614G changes the virus phenotype, the impact of the mutation on transmission, disease, and vaccine and therapeutic development are largely unknown.
Medical subject headings
- Betacoronavirus
- Coronavirus Infections
- Pandemics
- Pneumonia, Viral