Creating Space for Synaptic Formation-A New Role for Microglia in Synaptic Plasticity.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 32707091.
- Also identified by DOI 10.1016/j.cell.2020.06.042.
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Abstract
Memory formation is thought to occur in the brain through dynamic remodeling of the synaptic architecture between neurons. The cellular mechanisms underlying these dynamics remain unclear. In this issue, Nguyen et al. demonstrate a novel role for microglia in regulating synaptic formation by clearing extracellular matrix proteins that embed neurons.
Medical subject headings
- Microglia
- Neuronal Plasticity