Tertiary lymphoid tissue in kidneys: understanding local immunity and inflammation.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 32709287.
- Also identified by DOI 10.1016/j.kint.2020.04.026.
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Abstract
Tertiary lymphoid tissues are peripheral foci of immune activity that develop in kidneys and other peripheral organs in the context of chronic inflammation. In this issue of Kidney International, Sato and colleagues present a detailed characterization of tertiary lymphoid tissues in mouse and human kidneys in the context of acute kidney injury, chronic pyelonephritis, aging, and chronic kidney disease, showing the importance of nontraditional roles of B cells in the inflamed kidney microenvironment.
Medical subject headings
- Inflammation
- Lymphoid Tissue