Rtpca: an R package for differential thermal proximity coaggregation analysis.

Kurzawa, Nils; Mateus, André; Savitski, Mikhail M · Bioinformatics · 2021

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Abstract

Rtpca is an R package implementing methods for inferring protein-protein interactions (PPIs) based on thermal proteome profiling experiments of a single condition or in a differential setting via an approach called thermal proximity coaggregation. It offers user-friendly tools to explore datasets for their PPI predictive performance and easily integrates with available R packages. Rtpca is available from Bioconductor (https://bioconductor.org/packages/Rtpca). Supplementary data are available at Bioinformatics online.

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