Daratumumab (Anti-CD38) for Treatment of Disseminated Nontuberculous Mycobacteria in a Patient With Anti-Interferon-γ Autoantibodies.

Ochoa, Sebastian; Ding, Li; Kreuzburg, Samantha; Treat, Jennifer; Holland, Steven M; Zerbe, Christa S · Clin Infect Dis · 2021

case_report · Level V

Where this comes from

Abstract

Patients with autoantibodies to interferon-γ (IFN-γ) may develop severe nontuberculous mycobacterial infections. We describe the novel use of daratumumab in a patient with autoantibodies to IFN-γ who had progressive infection, resulting in clinical and radiographic improvement.

Medical subject headings