Triple A syndrome (Allgrove syndrome) - A journey from clinical symptoms to a syndrome.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 32754538.
- Also identified by DOI 10.4103/jfmpc.jfmpc_237_20 and PMC identifier 7380807.
- Licence recorded as CC BY-NC-SA.
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Abstract
Triple A syndrome (Allgrove syndrome) is characterized by a triad of specific features, namely, alacrimia, adrenal insufficiency, and achalasia cardia. It is a rare autosomal recessive disorder. In the present study, an 18-year-old boy was presented with complaints of decreased tears, darkening of the skin, difficulty in walking and standing up from sitting position, and difficulty in swallowing liquids. Adrenal insufficiency, alacrimia, achalasia, and neurological manifestations were confirmed with relevant laboratory investigations. His condition improved with steroids and artificial teardrops. However, a vigilant eye of the clinician for clinical clues of syndromic manifestation will help in early diagnosis and proper management.