Teaching Old Drugs New Tricks: Statins for COVID-19?
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 32755604.
- Also identified by DOI 10.1016/j.cmet.2020.07.006 and PMC identifier 7402379.
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Abstract
The COVID-19 pandemic has driven unprecedented efforts to identify existing treatments that can be quickly and effectively repurposed to reduce morbidity and mortality. In this issue of Cell Metabolism, Zhang et al. (2020) report an association between statin use and improved outcomes in a large observational study of hospitalized COVID-19 patients. Given the widespread availability, low cost, and safety of statins, this promising result should be further investigated in randomized controlled trials.
Medical subject headings
- Betacoronavirus
- Coronavirus Infections
- Drug Repositioning
- Hydroxymethylglutaryl-CoA Reductase Inhibitors
- Pneumonia, Viral