Anti-cytomegalovirus Immunoglobulin G Is Linked to CD4 T-cell Count Decay in Human Immunodeficiency Virus (HIV) Elite Controllers.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 32756974.
- Also identified by DOI 10.1093/cid/ciaa1129 and PMC identifier 8246824.
- Licence recorded as CC BY-NC-ND.
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Abstract
Elite controllers (ECs) are people living with human immunodeficiency virus (HIV) who spontaneously control viral replication without antiretroviral therapy. We observed that elevated anti-cytomegalovirus (CMV) immunoglobulin G (IgG) levels correlated with annual CD4 T-cell count decay in ECs independently of age, sex, and human leukocyte antigen (HLA) type. Elevated anti-CMV titers may favor disease progression in ECs.
Medical subject headings
- HIV Infections
- HIV-1