Quest for Ideal Composite Biomarkers for Response to Immunotherapies.

Swami, Umang; Nussenzveig, Roberto H; Agarwal, Neeraj · Clin Cancer Res · 2020

editorial · Level V

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Abstract

In the CheckMate 275 study, composite biomarkers appear to better predict response to immunotherapy over individual ones. Nevertheless, the path forward needs consensus guidelines for biomarker interpretation. Thereafter, prospective validation with real-time, serial biospecimen collection along with the development of composite biomarker models leads to the goal of personalized therapy.<i>See related article by Galsky et al., p. 5120</i>.

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