Choroid Plexus Organoids: Harnessing CSF Gatekeepers for Brain Therapeutics.

Xu, Huixin; Lehtinen, Maria K · Cell Stem Cell · 2020

editorial · Level V

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Abstract

Barrier properties of the choroid plexus (ChP) help protect the brain from the external world. In Science, Pellegrini et al. (2020) report the successful creation of human ChP organoids, which produce a cerebrospinal fluid-like secretion and recapitulate barrier functions, thereby inspiring new advances for targeted brain therapeutics.

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