Finding a Needle in a Haystack: Identification of a Beige Fat Progenitor.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 32763184.
- Also identified by DOI 10.1016/j.cell.2020.07.014.
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Abstract
Oguri and colleagues use single-cell RNA sequencing to identify a beige adipocyte precursor cell that gives rise to thermogenic adipocytes in subcutaneous adipose tissue. These beige fat progenitors are marked by PDGFRα, Sca1, and CD81 and proliferate upon activation of FAK-signaling in response to the cold and irisin.
Medical subject headings
- Adipocytes, Beige