Using Whole-genome Sequencing to Determine the Timing of Secondary Tuberculosis in British Columbia, Canada.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 32812027.
- Also identified by DOI 10.1093/cid/ciaa1224 and PMC identifier 8326569.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Combined with epidemiological data, whole-genome sequencing (WGS) can help better resolve individual tuberculosis (TB) transmission events to a degree not possible with traditional genotyping. We combine WGS data with patient-level data to calculate the timing of secondary TB among contacts of people diagnosed with active TB in British Columbia, Canada.
Medical subject headings
- Mycobacterium tuberculosis
- Tuberculosis