Moving Beyond BRCA-Incorporating Molecular Assays into Ovarian Cancer Trials.

McMullen, Michelle; Karakasis, Katherine; Oza, Amit M · Clin Cancer Res · 2020

editorial · Level V

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Abstract

PrOTYPE is a locked down assay validated to Institute of Medicine standards, using NanoString technology to classify high-grade serous ovarian cancer into four defined subgroups. Future directions will include prospective-retrospective analysis and prospective clinical validation to define the predictive role of this assay and its role in influencing treatment decisions.<i>See related article by Talhouk et al., p. 5411</i>.

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