SnapShot: FABP Functions.

Li, Bing; Hao, Jiaqing; Zeng, Jun; Sauter, Edward R · Cell · 2020

review · Level V

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Abstract

Fatty acid binding proteins (FABPs) serve as intracellular chaperones for fatty acids and other hydrophobic ligands inside cells. Recent studies have demonstrated new functions of individual members of the FABP family. This Snapshot describes the overall functions of FABPs in health and disease and highlights emerging roles of adipose FABP (A-FABP) and epidermal FABP (E-FABP) in the fields of obesity, chronic inflammation, and cancer development. To view this SnapShot, open or download the PDF.

Medical subject headings