Schlöndorff and Lee revealed crosstalk between glomerular cells and a role of BAMBI in diabetic kidney disease.

Nangaku, Masaomi · Kidney Int · 2020

editorial · Level V

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Abstract

The editorial team of Kidney International feels truly proud to publish Detlef Schlöndorff's legacy work. This seminal paper with Lee and Schlöndorff as joint senior authors revealed the importance of crosstalks between different glomerular cell types in diabetic kidney disease. Furthermore, they showed that bone morphogenetic protein (BMP) and activin membrane-bound inhibitor, an endogenous modulator of transforming growth factor-β signaling, plays a cell type-specific role and may be a good target for intervention against diabetic kidney disease.

Medical subject headings