Two Fatal Cases of Acute Liver Failure Due to HSV-1 Infection in COVID-19 Patients Following Immunomodulatory Therapies.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 32840571.
- Also identified by DOI 10.1093/cid/ciaa1246 and PMC identifier 7499514.
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Abstract
We report two fatal cases of acute liver failure secondary to herpes simplex virus 1 infection in COVID-19 patients, following tocilizumab and corticosteroid therapy. Screening for and prompt recognition of herpes simplex virus 1 reactivation in these patients, undergoing immunomodulatory treatment, may have potentially relevant clinical consequences.
Medical subject headings
- COVID-19
- Herpes Simplex
- Herpesvirus 1, Human
- Liver Failure, Acute