IBDkin: fast estimation of kinship coefficients from identity by descent segments.
other · Level V
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- Record sourced from PubMed, PMID 32844204.
- Also identified by DOI 10.1093/bioinformatics/btaa569 and PMC identifier 7750976.
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Abstract
Estimation of pairwise kinship coefficients in large datasets is computationally challenging because the number of related individuals increases quadratically with sample size. We present IBDkin, a software package written in C for estimating kinship coefficients from identity by descent (IBD) segments. We use IBDkin to estimate kinship coefficients for 7.95 billion pairs of individuals in the UK Biobank who share at least one detected IBD segment with length ≥ 4 cM. https://github.com/YingZhou001/IBDkin. Supplementary data are available at Bioinformatics online.
Medical subject headings
- Software