COVID-19 during pregnancy: non-reassuring fetal heart rate, placental pathology and coagulopathy.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 32853442.
- Also identified by DOI 10.1002/uog.22189 and PMC identifier 7461013.
- Licence recorded as CC BY-NC.
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Abstract
We report a case of a pregnant woman with COVID-19 who developed coagulopathy in the absence of severe clinical symptoms. A polymerase chain reaction test of a vaginal swab was positive for SARS-CoV-2 RNA, suggesting a possibility of perinatal transmission. Cesarean delivery was performed because of a non-reassuring fetal heart rate; the placenta showed increased perivillous fibrin deposition and intervillositis. Moreover, placental infection with SARS-CoV-2 was demonstrated by placental immunostaining. The findings suggest a possible relationship between placental fibrin deposition and chronic and acute intervillositis, non-reassuring fetal heart rate and coagulopathy in pregnant women with COVID-19. © 2020 The Authors. Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.
Medical subject headings
- Betacoronavirus
- Clinical Laboratory Techniques
- Coronavirus Infections
- Disseminated Intravascular Coagulation
- Pneumonia, Viral
- Pregnancy Complications, Hematologic
- Pregnancy Complications, Infectious