Are Seroprevalence Estimates for Severe Acute Respiratory Syndrome Coronavirus 2 Biased?
Where this comes from
- Record sourced from PubMed, PMID 32856712.
- Also identified by DOI 10.1093/infdis/jiaa523 and PMC identifier 7499591.
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Abstract
Biased seroprevalence estimates can occur using serological assays optimized with validation sets unrepresentative of disease spectrum in the general population. Correct interpretation of serosurveys for severe acute respiratory syndrome coronavirus 2 requires quantifying variations in sensitivity with disease severity and over time.
Medical subject headings
- COVID-19
- COVID-19 Testing
- SARS-CoV-2