Unraveling the Mechanism of the Antitumor Activity of Bacillus Calmette-Guérin.

Li, Roger; Gilbert, Scott M; Kamat, Ashish M · Eur Urol · 2021

editorial · Level V

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Abstract

Our understanding of the mechanism of bacillus Calmette-Guérin (BCG) in controlling urothelial carcinoma is still evolving. Studies have revealed a complex and multifaceted immune response. BCG-elicited adaptive antitumor immunity directed towards tumor antigens could have major implications for trial design.

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