Associations of CT evaluations of antigravity muscles, emphysema and airway disease with longitudinal outcomes in patients with COPD.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 32868293.
- Also identified by DOI 10.1136/thoraxjnl-2020-215085.
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Abstract
Multiple CT indices are associated with disease progression and mortality in patients with COPD, but which indices have the strongest association remain unestablished. This longitudinal 10-year observational study (n=247) showed that the emphysema severity on CT is more closely associated with the progression of airflow limitation and that a reduction in the cross-sectional area of erector spinae muscles (ESM<sub>CSA</sub>) on CT is more closely associated with mortality than the other CT indices, independent of patient demographics and pulmonary function. ESM<sub>CSA</sub> is a useful CT index that is more closely associated with long-term mortality than emphysema and airway disease in patients with COPD.
Medical subject headings
- Airway Remodeling
- Pulmonary Disease, Chronic Obstructive
- Pulmonary Emphysema
- Respiratory Muscles
- Tomography, X-Ray Computed