Alpha-Ketoglutarate, the Metabolite that Regulates Aging in Mice.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 32877686.
- Also identified by DOI 10.1016/j.cmet.2020.08.009 and PMC identifier 8191137.
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Abstract
In this issue of Cell Metabolism, Asadi Shahmirzadi et al. (2020) demonstrate that late-onset dietary supplementation with calcium alpha-ketoglutarate results in increased survival, compressed morbidity, and reduced frailty in mice. The study provides further evidence for critical links between metabolism, inflammation, and aging.
Medical subject headings
- Ketoglutaric Acids
- Longevity