Vascular Changes in Cancer Treatment-Seeing Is Believing.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 32878865.
- Also identified by DOI 10.1158/0008-5472.CAN-20-2361.
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Abstract
Understanding the effects of novel cancer drugs on the tumor microenvironment will be crucial for their successful use in patients. In this issue of <i>Cancer Research</i>, Ghosh and colleagues discuss the effect of two promising heme-targeting agents on the vascular network in mouse models of lung cancer, utilizing emerging optoacoustic imaging approaches. The findings demonstrating significant, dynamic modulation of tumor hypoxia with the heme-targeting drug treatments create important opportunities for image-guided combination therapy.<i>See related article by Ghosh et al., p. 3542</i>.
Medical subject headings
- Neoplasms
- Oxygen