SnapShot: β-Arrestin Functions.

Ahn, Seungkirl; Shenoy, Sudha K; Luttrell, Louis M; Lefkowitz, Robert J · Cell · 2020

review · Level V

Where this comes from

Abstract

The arrestins are ubiquitously expressed adaptor proteins that orchestrate transmembrane signaling cascades triggered by the 7-transmembrane G protein-coupled receptors. While originally discovered as proteins that block receptor-G protein coupling, arrestins are now appreciated for their expanding repertoire of dynamic protein interactions and cellular functions.

Medical subject headings