Diabetes and COVID-19: A pooled analysis related to disease severity and mortality.
meta_analysis · Level I
Where this comes from
- Record sourced from PubMed, PMID 32891525.
- Also identified by DOI 10.1016/j.pcd.2020.08.015 and PMC identifier 7456278.
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Abstract
Globally, COVID-19 has become a major concern for the diabetic community. We conducted a pooled analysis and constructed a forest plot for the association between diabetes and COVID-19 progression in 47 studies. A random effects meta-analysis (Mantel-Haenszel method) was conducted to estimate the outcomes effect size as odds ratios (OR) and 95% confidence intervals (CI) using Review Manager Software version 5.3. COVID-19 patients with diabetes have a significantly higher risk of disease severity (OR=2.20, 95% CI=1.69-2.86, p<0.00001) and associated mortality outcomes (OR=2.52, 95% CI=1.93-3.30, p=<0.00001).
Medical subject headings
- COVID-19
- Diabetes Mellitus
- Pandemics