Genomic Screening for Malignant Hyperthermia Susceptibility.

Biesecker, Leslie G; Dirksen, Robert T; Girard, Thierry; Hopkins, Philip M; Riazi, Sheila; Rosenberg, Henry; Stowell, Kathryn; Weber, James · Anesthesiology · 2020

review · Level V

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Abstract

It is timely to consider the utility and practicability of screening for malignant hyperthermia susceptibility using genomic testing. Here the authors pose a simple, but bold question: what would it take to end deaths from malignant hyperthermia? The authors review recent advances and propose a scientific and clinical pathway toward this audacious goal to provoke discussion in the field.

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