Disassembling peptide-based fibres by switching the hydrophobic-hydrophilic balance.
basic_science · Level V
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- Record sourced from PubMed, PMID 32900034.
- Also identified by DOI 10.1039/b708847g.
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Abstract
Amyloid-like model peptides, modified on the N-terminus with an alkyl tail and on the C-terminus with a PEG chain, yielded fibres that were susceptible to triggered disassembly by removal of the alkyl chain, which affected the hydrophobic-hydrophilic balance.