Extending the window for thrombolysis for treatment of acute ischaemic stroke during pregnancy: a review.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 32920999.
- Also identified by DOI 10.1111/1471-0528.16495.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Historically, safety of intravenous recombinant tissue plasminogen activator (IV rt-PA) for the treatment of acute ischaemic stroke (AIS) is limited to use within 4.5 hours from symptom onset. Recent studies suggest the treatment window may be extended when patients have salvageable brain tissue on advanced neuroimaging. This paper describes a novel use of IV rt-PA for treatment of AIS in a pregnant patient within an extended-time window (>4.5 hours, and <9 hours) based on advanced neuroimaging with a favourable outcome. TWEETABLE ABSTRACT: Novel use of IV rt-PA for treatment of AIS in pregnancy within an extended-time window based on advanced imaging with a favourable outcome.
Medical subject headings
- Fibrinolytic Agents
- Ischemic Stroke
- Pregnancy Complications, Cardiovascular
- Thrombolytic Therapy
- Tissue Plasminogen Activator