Thyroid Stimulating Hormone Stability in Patients Prescribed Synthetic or Desiccated Thyroid Products: A Retrospective Study.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 32928762.
- Also identified by DOI 10.1370/afm.2545 and PMC identifier 7489980.
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Abstract
The purpose of this retrospective matched-cohort study was to evaluate the stability of thyroid stimulating hormone (TSH) in patients using synthetic compared with desiccated thyroid products. Patients using a thyroid product for the treatment of hypothyroidism were matched 1:1 on age, sex, race/ethnicity, and had a follow-up period of 3 years after the index date. The primary outcome was percent of in-range TSH values. Over 3 years, TSH values in both groups were in-range 79% of the time (<i>P</i> = 0.905). Our results showed no difference in longitudinal TSH stability between desiccated thyroid products and synthetic levothyroxine.
Medical subject headings
- Hypothyroidism
- Thyroid (USP)
- Thyrotropin
- Thyroxine