SnapShot: The Regulatory Genome.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 32946787.
- Also identified by DOI 10.1016/j.cell.2020.07.041 and PMC identifier 8722530.
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Abstract
Enhancers switch genes on and off in response to a variety of intrinsic and external cellular signals. They are the cornerstone of gene regulation and the most pervasive constituents of the regulatory genome. Sequence polymorphisms in enhancer DNAs are a major source of population diversity and predilection to disease. To view this SnapShot, open or download the PDF.
Medical subject headings
- Enhancer Elements, Genetic
- Gene Expression Regulation