Prolonged Tracheal Intubation and the Association Between Patent Ductus Arteriosus and Bronchopulmonary Dysplasia: A Secondary Analysis of the PDA-TOLERATE trial.

Clyman, Ronald I; Kaempf, Joseph; Liebowitz, Melissa; Erdeve, Omer; Bulbul, Ali; Håkansson, Stellan; Lindqvist, Johanna; Farooqi, Aijaz et al. · J Pediatr · 2021

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Abstract

In the PDA-TOLERATE trial, persistent (even for several weeks) moderate to large patent ductus arteriosus (PDA) was not associated with an increased risk of BPD when the infant required <10 days of intubation. However, in infants requiring intubation for ≥10 days, prolonged PDA exposure (≥11 days) was associated with an increased risk of moderate/severe BPD.

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