Postoperative negative pressure wound therapy is associated with decreased surgical site infections in all lower extremity amputations.
retrospective_cohort · Level III
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- Record sourced from PubMed, PMID 32999539.
- Also identified by DOI 10.1016/j.jor.2020.09.005 and PMC identifier 7508917.
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Abstract
We hypothesize that Negative Pressure Wound Therapy (NPWT) is associated with a lower incidence of surgical site infection (SSI) in lower extremity amputations (LEAs), a potentially devastating complication. NSQIP database from 2011 to 2018 was queried to identify all-level LEAs. Cases using NPWT were identified. One-to-one nearest-neighbor propensity score matching was performed using a binary logistic regression on NPWT status controlling for patient comorbidities. NPWT was used in 133 of 5237 total LEAs (2.54%). Compared to propensity score-matched controls, they had significantly fewer SSIs (1.50% vs. 8.27%). NPWT was associated with lower incidence of SSI.