COVID-19 and the kidney.

Hassanein, Mohamed; Radhakrishnan, Yeshwanter; Sedor, John; Vachharajani, Tushar; Vachharajani, Vidula T; Augustine, Joshua; Demirjian, Sevag; Thomas, George · Cleve Clin J Med · 2020

review · Level V

Where this comes from

Abstract

COVID-19 is primarily considered a respiratory illness, but the kidney may be one of the targets of SARS-CoV-2 infection, since the virus enters cells through the angiotensin-converting enzyme 2 receptor, which is found in abundance in the kidney. Information on kidney involvement in COVID-19 is limited but is evolving rapidly. This article discusses the pathogenesis of acute kidney injury (AKI) in COVID-19, its optimal management, and the impact of COVID-19 on patients with chronic kidney disease, patients with end-stage kidney disease on dialysis, and kidney transplant recipients.

Medical subject headings