Solving the Puzzle of Immune Tolerance for β-Cell Replacement Therapy for Type 1 Diabetes.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 33007232.
- Also identified by DOI 10.1016/j.stem.2020.09.008.
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Abstract
Type 1 diabetes mellitus results from autoimmune destruction of pancreatic β cells. Insulin treatment is often inadequate in preventing devastating complications. Replacing β cells using stem cell-derived islets while fostering immune tolerance, exemplified in Yoshihara et al., holds the promise of a curative therapy for this disease.
Medical subject headings
- Diabetes Mellitus, Type 1
- Insulin-Secreting Cells
- Islets of Langerhans