Balancing Expectations for Success in Stem Cell-Based Clinical Trials for Parkinson's Disease.

Lindvall, Olle · Cell Stem Cell · 2020

review · Level V

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Abstract

Upcoming clinical trials assessing transplantation of stem cell-derived dopaminergic neurons into the striatum in patients with Parkinson's disease could generate groundbreaking results on neuronal replacement in the human brain. However, as highlighted here, the road toward a clinically competitive treatment for this multisystem disorder will probably be long and winding.

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