Mitochondrial Ejection for Cardiac Protection: The Macrophage Connection.
Level V
Where this comes from
- Record sourced from PubMed, PMID 33027673.
- Also identified by DOI 10.1016/j.cmet.2020.09.014.
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Abstract
Mitochondrial dysfunction is a hallmark of heart disease. Nicolás-Ávila et al. (2020) now find that cardiomyocytes eject dysfunctional mitochondria in exopher vesicles, which require elimination by specialized heart-resident macrophages, altogether supporting proper heart function.
Medical subject headings
- Heart Failure
- Mitochondria