Antifungal Susceptibility Does Not Correlate With Fungal Clearance or Survival in AIDS-Associated Cryptococcal Meningitis.
rct · Level II
Where this comes from
- Record sourced from PubMed, PMID 33051650.
- Also identified by DOI 10.1093/cid/ciaa1544 and PMC identifier 8561241.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
We investigated the value of susceptibility testing in predicting response in AIDS-associated cryptococcal meningitis using clinical isolates from a randomized controlled trial of antifungal treatment (amphotericin monotherapy, amphotericin with flucytosine, or amphotericin with fluconazole). We found no correlation between antifungal susceptibility and either early or late survival, or fungal clearance.
Medical subject headings
- Acquired Immunodeficiency Syndrome
- Meningitis, Cryptococcal