Globus pallidus internus activity during simultaneous bilateral microelectrode recordings in status dystonicus.
case_report · Level V
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- Record sourced from PubMed, PMID 33052494.
- Also identified by DOI 10.1007/s00701-020-04618-w.
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Abstract
Limited data are available regarding the electrophysiology of status dystonicus (SD). We report simultaneous microelectrode recordings (MERs) from the globus pallidus internus (GPi) of a patient with SD who was treated with bilateral deep brain stimulation (DBS). Mean neuronal discharge rate was of 30.1 ± 10.9 Hz and 38.5 Hz ± 11.1 Hz for the right and left GPi, respectively. On the right side, neuronal electrical activity was completely abolished at the target point, whereas the mean burst index values showed a predominance of bursting and irregular activity along trajectories on both sides. Our data are in line with previous findings of pallidal irregular hypoactivity as a potential electrophysiological marker of dystonia and thus SD, but further electrophysiological studies are needed to confirm our results.
Medical subject headings
- Deep Brain Stimulation
- Dystonic Disorders
- Globus Pallidus