The transcriptomic signature of the aging podocyte.
Where this comes from
- Record sourced from PubMed, PMID 33126968.
- Also identified by DOI 10.1016/j.kint.2020.08.004 and PMC identifier 9380427.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Aging is the strongest independent risk factor for chronic kidney disease. Glomerular epithelial cells are unable to proliferate and have limited ability to renew; therefore, podocytes must maintain a delicate intracellular homeostasis that enables them to function and adapt to stress endured during the human life span. Here, Wang et al. performed unbiased transcriptomic analysis of aging podocytes and identified important novel regulators.
Medical subject headings
- Kidney Diseases
- Podocytes