A Blueprint for Characterizing Senescence.

Roy, Ananda L; Sierra, Felipe; Howcroft, Kevin; Singer, Dinah S; Sharpless, Norman; Hodes, Richard J; Wilder, Elizabeth L; Anderson, James M · Cell · 2020

review · Level V

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Abstract

Given the heterogeneity of senescent cells, our knowledge of both the drivers and consequences of cellular senescence in tissues and organs remains limited, as is our understanding of how this process could be harnessed for human health. Here we identified five broad areas that would help propel the field forward.

Medical subject headings