A Selective Sweep Conceals a MicroRNA with Broad Metabolic Effects.

Mathieson, Iain; Grant, Struan F A · Cell Metab · 2020

basic_science · Level V

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Abstract

The need for discovering new genes driving metabolic disease susceptibility is clear; even clearer is the need for their subsequent functional characterization. A new paper reports a role for miR-128-1 in metabolic control through a series of elegant mouse studies, and an intriguing hypothesis about its "thrifty" role in metabolism.

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