A "Switch" in Time through Genes Aligned: Unraveling the Genomic Landscape of HSC Development.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 33157043.
- Also identified by DOI 10.1016/j.stem.2020.10.011.
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Abstract
Seeking to define the "switch" from fetal to adult hematopoiesis, Li et al. (2020) performed extensive genomic and epigenomic profiling of hematopoietic stem and progenitor cells across ontogeny (as explored in this issue of Cell Stem Cell). Gradual and stochastic changes in genomic and epigenomic regulation suggest the absence of any specific regulator.
Medical subject headings
- Hematopoietic Stem Cells
- Single-Cell Analysis