Treatment of Differentiated Thyroid Cancer and Recurrent Laryngeal Nerve Function with 131 Iodine Based on Positron Emission Tomography/Computed Tomography Image Segmentation Algorithm.

Abstract

Based on the positron emission tomography (PET) computed tomography (CT) image segmentation algorithm, this article explores the application of PET/CT in the recurrence and metastasis of thyroid cancer after differentiated thyroid cancer (DTC). In this study, 132 patients with DTC combined with ¹³¹I treatment underwent PET/CT whole-body imaging and ¹³¹I whole-body scan (¹³¹I-WBS), and the serum thyroglobulin (Tg) level was measured at the same time. Among 54 Tg-positive patients, 49 were positive for ¹³¹I-WBS and 32 were positive for PET/CT imaging. Of the 15 Tg-negative patients, ¹³¹I-WBS and PET/CT imaging were negative. Three patients with ¹³¹I-WBS suggesting residual thyroid tumors were all positive in PET/CT examinations; 7 patients with ¹³¹I-WBS suggesting lymph node metastasis were all positive in PET/CT examinations, and in ¹³¹I, PET/CT imaging in WBS-negative patients showed 6 lung metastases and 3 bone metastases. PET/CT and ¹³¹I scans are similar in the diagnosis of residual thyroid and lymph node metastasis, but PET/CT has more advantages than does the ¹³¹I scan in the diagnosis of bone metastasis and lung metastasis. PET/CT can still find other benign and malignant lesions, which is of great value in the restaging of DTC. The imaging effect of WBS lung lesions in older patients is not good. The presence of stripe, calcification, and patch shadows in the lungs is not conducive to the imaging of WBS lung metastases. Lung strips and calcification affect the WBS lung main factors for imaging of metastases.