SnapShot: APC/T Cell Immune Checkpoints.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 33186524.
- Also identified by DOI 10.1016/j.cell.2020.10.007.
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Abstract
Immune checkpoints are key regulatory mechanisms integral to the maintenance of self-tolerance and execution of antigen-specific immune responses. In recent years, they have been leveraged to treat both autoimmune disease and various forms of cancer with much success. This SnapShot illustrates known immune checkpoint interactions in APC-mediated T cell modulation. To view this SnapShot, open or download the PDF.
Medical subject headings
- Antigen-Presenting Cells
- Immune Checkpoint Proteins
- T-Lymphocytes