Secondary Attack Rate and Family Clustering of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Children of Healthcare Workers With Confirmed Coronavirus Disease 2019 (COVID-19).

Ladhani, Shamez N; Andrews, Nick; Aiano, Felicity; Baawuah, Frances; Amin-Chowdhury, Zahin; Brown, Kevin E; Amirthalingam, Gayatri; Ramsay, Mary E et al. · Clin Infect Dis · 2021

cross_sectional · Level IV

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Abstract

We measured serum SARS-CoV-2 antibodies in 215 children of healthcare workers to estimate secondary attack rates. Twenty-one families had a parent with confirmed COVID-19. There was strong evidence of family clustering (P < .001): 20/21 (95.2%) children were seropositive in 9 families and none of 23 children in 12 other families.

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